"选择性β1受体阻断剂的结构特点是
" "A:在苯环上连有甲氧乙基
" "B:在丙醇胺侧链N上连有取代基
" "C:在丙醇胺侧链的对位连有取代基
" "D:在丙醇胺侧链的邻位连有取代基
" "E:在丙醇胺侧链的间位连有取代基
" "答案:C
"
"洛伐他汀主要用于
" "A:治疗心律不齐
" "B:抗高血压
" "C:降低血中三酰甘油含量
" "D:降低血中胆固醇含量
" "E:治疗心绞痛
" "答案:D
"
"下列药物中哪个不具有抗高血压作用
" "A:氯贝丁酯
" "B:甲基多巴
" "C:盐酸普萘洛尔
" "D:利舍平
" "E:卡托普利
" "答案:A
"
"马来酸依那普利可用于
" "A:治疗心绞痛
" "B:治疗心律失常
" "C:降血酯
" "D:抗高血压
" "E:治疗心力衰竭
" "答案:B
"
"用于治疗脑血管疾病的钙拮抗剂是
" "A:硝苯地平
" "B:桂利嗪
" "C:盐酸地尔硫卓
" "D:尼群地平
" "E:氨氯地平
" "答案:B
"
"下列用于抗心律失常的药物是
" "A:非诺贝特
" "B:氨力农
" "C:硝酸异山梨醇脂症
" "D:盐酸美西律
" "E:双嘧达莫
" "答案:D
"
"氟伐他汀主要用于治疗
" "A:高甘油血脂症
" "B:高胆固醇血症
" "C:高磷脂血症
" "D:心绞痛
" "E:心律不齐
" "答案:B
"
"下列药物类型中,哪一类没有强心作用
" "A:强心苷类
" "B:拟交感胺类
" "C:β受体阻断剂
" "D:磷酸二酯酶抑制剂
" "E:钙敏化剂
" "答案:C
"
"心血管系统药物根据临床症状分有哪几类
" "A:降血脂类,降压类,止血类
" "B:降压类,降血酯类,抗心绞痛类,抗心律失常类,强心药
" "C:抗心绞痛类,降压类,强心苷类
" "D:抗脑溢血类,降血脂类,抗心力衰竭类,强心苷类
" "E:抗动脉粥样硬化药,降血脂药，DHP类Ca-A类
" "答案:B
"
"卡托普利是
" "A:中枢性降压药
" "B:血管扩张药
" "C:作用于交感神经的降压药
" "D:羟甲戊二酰辅酶A还原酶抑制剂
" "E:血管紧张素转化酶抑制剂
" "答案:E
"
"化学名称为1-[3-巯基-(2S)-2-甲基-1-氧代丙基]-L-脯氨酸的药物是
" "A:尼莫地平
" "B:氯贝丁酯
" "C:卡托普利
" "D:硝苯地平
" "E:普萘洛尔
" "答案:C
"
"下列各种类型药物中哪一种具有降血脂的作用
" "A:羟甲戊二酰辅酶A还原酶抑制剂
" "B:血管紧张素转化酶(ACE)抑制剂
" "C:强心苷类
" "D:钙通道阻滞剂
" "E:磷酸二酯酶抑制剂
" "答案:A
"
"氯贝丁酯在储存中
" "A:可发生氧化反应
" "B:可发生水解反应
" "C:可发生重排反应
" "D:遇光可缓慢分解生成对氯苯酚
" "E:遇潮湿空气可缓慢分解成对氯苯酚
" "答案:D
"
"下列叙述中,哪条不符合利舍平的性质
" "A:结构中含有吲哚环
" "B:结构中含有两个酯基
" "C:在酸碱催化下发生水解,水解产物失去活性
" "D:具有温和而持久的降压作用
" "E:对光不稳定,应避光保存
" "答案:C
"
"氯贝丁酯的化学名为
" "A:2-甲基-2-(3-氯苯氧基)丙酸丁酯
" "B:2-甲基-2-(4-氯苯氧基)丙酸乙酯
" "C:2-甲基-2-(2-氯苯基)丙酸丁酯
" "D:2-甲基-2-(2-氯苯氧基)丙酸乙酯
" "E:2-甲基-2-(4-氯苯氧基)丙酸丁酯
" "答案:B
"
"盐酸地尔硫卓的母核结构为
" "A:1,4-苯并二氮卓
" "B:1,5-苯并二氮卓
" "C:1,4-苯并硫氮卓
" "D:1,5-苯并硫氮卓
" "E:二苯并硫氮卓
" "答案:D
"
"氨力农的作用机制为
" "A:血管紧张素转化酶抑制剂
" "B:β内酰胺酶抑制剂
" "C:环氧酶抑制剂
" "D:磷酸二酯酶抑制剂
" "E:黏肽转肽酶抑制剂
" "答案:D
"
"硝苯地平的化学名为
" "A:2,6-二甲基-4-(2-硝基苯基)-1,4-二氢-3,5-吡啶二甲酸二甲酯
" "B:2,6-二甲基-4-(3-硝基苯基)-1,4-二氢-3,5-吡啶二甲酸二甲酯
" "C:2,6-二甲基-4-(2-硝基苯基)-1,4-二氢-3,5-吡啶二甲酸甲乙酯
" "D:2,6-二甲基-4-(3-硝基苯基)-1,4-二氢-3,5-吡啶二甲酸甲乙酯
" "E:2,4-二甲基-4-(2-硝基苯基)-1,4-二氢-3,5-吡啶二甲酸二甲酯
" "答案:A
"
"与盐酸美西律结构式以及药理活性相似的药物是
" "A:盐酸利多卡因
" "B:盐酸哌替啶
" "C:盐酸美沙酮
" "D:盐酸普罗帕酮
" "E:盐酸胺碘酮
" "答案:A
"
"氨氯地平的化学名为
" "A:(±)2-[(2-氨基乙氧基)甲基]-4-（2-氯苯基）-1，4-二氢-6-甲基-3，5-
" "B:1,4-二氢-2,6-二甲基-4-(3-硝基苯基)-3,5-吡啶二甲酸甲乙酯
" "C:1,4-二氢-2,6-二甲基-4-(2-硝基苯基)-3,5〖CD*2〗吡啶二甲酸甲乙酯
" "D:1,4-二氢-2,6-二甲基-4-(3-硝基苯基)-3,5-吡啶二甲酸-2-甲氧乙基-1
" "E:1,4-二氢-2,6-二甲基-4-(2-硝基苯基)-3,5-吡啶二甲酸-3-(2-甲基丙基
" "答案:A
"
"下列哪项描述与利舍平的结构不符
" "A:含吲哚环
" "B:3位的氢为α构型
" "C:含有2个酯基
" "D:含有甲氧基
" "E:含1个哌啶环
" "答案:B
"
"羟甲戊二酰辅酶A还原酶抑制剂可以
" "A:抑制体内cAMP的降解
" "B:抑制血管紧张素Ⅰ向血管紧张素Ⅱ的转化
" "C:阻止内源性胆固醇的合成
" "D:降低血中三酰甘油含量
" "E:促进胆固醇的排泄
" "答案:C
"
"下列哪个药物的结构中含有苯并呋喃环
" "A:盐酸普罗帕酮
" "B:盐酸胺碘酮
" "C:呋塞米
" "D:盐酸美西律
" "E:氯噻酮
" "答案:B
"
"盐酸维拉帕米属于
" "A:芳烷基胺类钙拮抗剂
" "B:羟甲戊二酰辅酶A还原酶抑制剂
" "C:苯氧乙酸类降血脂药
" "D:三苯哌嗪类抗心绞痛药
" "E:髓襻利尿药
" "答案:A
"
"硝苯地平在临床上用于
" "A:降血脂
" "B:心律失常、急慢性心力衰竭
" "C:阵发性心动过速、期前收缩
" "答案:C
"
"属于非经典的β-内酰胺类抗生素的药物是
" "A:阿奇霉素
" "B:亚胺培南
" "C:头孢克络
" "D:舒巴坦
" "E:阿米卡星
" "答案:B
"
"头孢菌素分子结构中含有手性碳的数目是
" "A:2个
" "B:3个
" "C:4个
" "D:5个
" "E:1个
" "答案:A
"
"青霉素分子结构中含有手性碳的构型是
" "A:2R，5S
" "B:2S，5R
" "C:2S，RR，6R
" "D:2R，5S，6S
" "E:2R，5R
" "答案:C
"
"以多氢化并四苯为母体的药物是
" "A:罗红霉素
" "B:麦迪霉素
" "C:盐酸克林霉素
" "D:盐酸美他环素
" "E:氯霉素
" "答案:D
"
"下列药物不属于抗寄生虫药物的是
" "A:甲硝唑
" "B:青蒿琥酯
" "C:磷酸氯喹
" "D:氟哌酸
" "E:丙硫咪唑
" "答案:D
"
"下列药物属于抗寄生虫药物的是
" "A:吡喹酮
" "B:氧氟沙星
" "C:地巴唑
" "D:头孢氨苄
" "E:克拉维酸
" "答案:A
"
"下列药物中属于抗疟疾药的是
" "A:甲硝唑
" "B:丙硫咪唑
" "C:磷酸伯氨喹
" "D:枸橼酸哌嗪
" "E:阿苯达唑
" "答案:C
"
"下列药物中属于抗血吸虫病的药物是
" "A:甲硝唑
" "B:丙硫咪唑
" "C:吡喹酮
" "D:枸橼酸哌嗪
" "E:阿苯达唑
" "答案:C
"
"下列药物中属于驱肠虫的药物是
" "A:替硝唑
" "B:丙硫咪唑
" "C:青蒿素
" "D:枸橼酸哌嗪
" "E:磷酸氯喹
" "答案:D
"
"下列药物中具有抗丝虫作用的药物是
" "A:枸橼酸乙胺嗪
" "B:奥硝唑
" "C:丙硫咪唑
" "D:青蒿素
" "E:奎宁
" "答案:A
"
"下列药物中具有抗阿米巴病和滴虫病作用的药物是
" "A:替硝唑
" "B:吡喹酮
" "C:青蒿素
" "D:枸橼酸哌嗪
" "E:磷酸氯喹
" "答案:A
"
"下列抗疟疾药中直接从天然植物提取的药物是
" "A:二氢青蒿素
" "B:磷酸氯喹
" "C:磷酸伯氨喹
" "D:青蒿琥酯
" "E:奎宁
" "答案:E
"
"我国科学家发明的鹤草酚的药理作用是
" "A:抗丝虫药
" "B:抗疟疾药
" "C:驱肠虫药
" "D:抗绦虫药
" "E:抗滴虫药
" "答案:D
"
"鹤草酚在结构上属于
" "A:哌嗪类
" "B:咪唑类
" "C:酚类
" "D:喹啉类
" "E:萜类
" "答案:C
"
"根据奎宁的代谢设计的抗疟疾药是
" "A:喹尼丁
" "B:氯喹
" "C:优奎宁
" "D:辛可宁
" "E:甲氟喹
" "答案:E
"
"临床上使用的吡喹酮的化学结构是一个
" "A:混旋体
" "B:消旋体
" "C:左旋体
" "D:右旋体
" "E:混合物
" "答案:B
"
"下列哪项叙述与二盐酸奎宁的结构不符
" "A:含喹啉环
" "B:含异喹啉环
" "C:含喹核碱
" "D:含醇羟基
" "E:含乙烯基
" "答案:B
"
"蒿甲醚的抗疟作用为青蒿素的10~20倍，这是因为
" "A:过氧桥断裂，稳定性增加
" "B:脂溶性较大，吸收和中枢渗透率高于青蒿素
" "C:蒿甲醚发生了异构化，对疟原早虫的毒性更强
" "D:蒿甲醚为广谱抗虫药
" "E:蒿甲醚作用于疟原虫的各个生长期
" "答案:B
"
"青蒿素结构中
" "A:含苯环
" "B:含过氧键
" "C:含双键
" "D:含嘧啶环
" "E:含喹啉环
" "答案:B
"
"枸橼酸乙胺嗪临床应用是
" "A:抗高血压
" "B:抗丝虫病
" "C:驱蛔虫和蛲虫
" "D:利尿
" "E:抗疟
" "答案:B
"
"抗肠虫药按照结构类型主要可分为
" "A:咪唑类、嘧啶类、三萜类和酚类
" "B:哌嗪类、嘧啶类、三萜类和酚类
" "C:咪唑类、哌嗪类、嘧啶类
" "D:咪唑类、哌嗪类、三萜类和酚类
" "E:咪唑类、哌嗪类、嘧啶类、三萜类和酚类
" "答案:E
"
"同时具有免疫调节作用的广谱驱虫药是
" "A:阿苯达唑
" "B:鹤草酚
" "C:盐酸左旋咪唑
" "D:枸橼酸哌嗪
" "E:噻嘧啶
" "答案:C
"
"与氢氧化钠水溶液共沸开环产生巯基，遇亚硝基铁氰化钠反应生成红色的药物是
" "A:阿苯达唑
" "B:吡喹酮
" "C:乙胺嘧啶
" "D:甲硝唑
" "E:盐酸左旋咪唑
" "答案:E
"
"抗滴虫病的药物是
" "A:青蒿素
" "B:甲硝唑
" "C:磷酸氯喹
" "D:二盐酸奎宁
" "E:枸橼酸乙胺嗪
" "答案:B
"
"化学名称为6-乙基-5-（4-氯苯基）-2，4-嘧啶二胺的药物是
" "A:甲硝唑
" "B:美法仑
" "C:白消安
" "D:卡莫氟
" "E:盐酸阿糖胞苷
" "答案:D
"
"阿昔洛韦的化学名为
" "A:9-(2-羟乙氧甲基)鸟嘌呤
" "B:9-(2-羟丙氧甲基)鸟嘌呤
" "C:9-(2-羟乙氧乙基)鸟嘌呤
" "D:9-(2-羟丙氧乙基)鸟嘌呤
" "E:9-(2-羟乙氧丙基)鸟嘌呤
" "答案:A
"
"化学名为α-(2,4-二氟苯基)-α-(1H-1,2,4-三唑-1-基甲基)-1H-1,2,4-三唑-1-基乙醇的药物名称为
" "A:克霉唑
" "B:氟康唑
" "C:酮康唑
" "D:咪康唑
" "E:以上都不是
" "答案:B
"
"利巴韦林的化学名为
" "A:1-β-D-呋喃核糖-1H-咪唑-3-羧酰胺
" "B:1-β-D-呋喃核糖-1,3,4-噻二唑-2-乙酰胺
" "C:1-β-D-呋喃核糖-1H-1,2,4-三氮唑-3-羧酰胺
" "D:1-α-D-葡吡喃糖-1H-1,2,4-三氮唑-3-羧酰胺
" "E:1-β-D-呋喃核糖-1H-1,2,3,4-四氮唑-5-羧酰胺
" "答案:C
"
"阿昔洛韦临床上主要用于
" "A:广谱抗病毒药
" "B:抗深部真菌感染药
" "C:抗革兰阴性菌感染药
" "D:厌氧菌感染
" "E:泌尿系统感染
" "答案:A
"
"抗病毒药物按其作用机制可分为
" "A:核苷类和非核苷类
" "B:金刚烷胺类、干扰素及干扰素诱导剂
" "C:逆转录酶抑制剂和蛋白酶抑制剂
" "D:嘧啶核苷类和胞嘧啶核苷类
" "E:抑制病毒复制的药物，干扰病毒核酸复制的药物，影响核糖体翻译的药物
" "答案:E
"
"抗艾滋病药物按其作用机制可分为
" "A:核苷类和非核苷类
" "B:金刚烷胺类、干扰素及干扰素诱导剂
" "C:逆转录酶抑制剂和蛋白酶抑制剂
" "D:嘧啶核苷类和胞嘧啶核苷类
" "E:抑制病毒复制的药物，干扰病毒核酸复制的药物，影响核糖体翻译的药物
" "答案:C
"
"金刚烷胺类抗病毒药物作用在于
" "A:抑制病毒复制
" "B:影响核糖体翻译
" "C:干扰病毒核酸复制
" "D:竞争性地抑制胸苷激酶和DNA聚合酶
" "E:具有以上所有作用
" "答案:A
"
"阿昔洛韦的抗病毒作用在于
" "A:抑制病毒复制
" "B:影响核糖体翻译
" "C:抑制蛋白酶活性
" "D:竞争性地抑制胸苷激酶和DNA聚合酶
" "E:具有以上所有作用
" "答案:D
"
"碘苷的抗病毒作用在于
" "A:抑制病毒复制
" "B:影响核糖体翻译
" "C:抑制蛋白酶活性
" "D:竞争性地抑制DNA聚合酶
" "E:具有以上所有作用
" "答案:D
"
"第一个上市的治疗艾滋病的蛋白酶抑制剂是
" "A:AZT
" "B:沙奎那韦
" "C:碘苷
" "D:金刚烷胺
" "E:阿昔洛韦
" "答案:B
"
"第一个临床上有效的核苷类抗病毒药物是
" "A:AZT
" "B:DDC
" "C:碘苷
" "D:金刚烷胺
" "E:阿昔洛韦
" "答案:C
"
"下列药物中属于非核苷类抗病毒药物的是
" "A:AZT
" "B:DDC
" "C:碘苷
" "D:金刚烷胺
" "E:阿昔洛韦
" "答案:D
"
"艾滋病（AIDS）的全称是
" "A:先天性免疫缺陷综合征
" "B:获得性免疫缺陷综合征
" "C:传染性免疫缺陷综合征
" "D:HIV缺陷综合征
" "E:以上叫法都对
" "答案:B
"
"HIV-I属于
" "A:流感病毒
" "B:A型流感病毒
" "C:疱疹病毒
" "D:逆转录病毒
" "E:乙肝病毒
" "答案:D
"
"FDA批准的第一个治疗艾滋病及其综合征的药物是
" "A:阿昔洛韦
" "B:沙奎那韦
" "C:AZT
" "D:DDC
" "E:磺苷
" "答案:C
"
"核苷类抗病毒药物设计基于
" "A:代谢拮抗原理
" "B:电子等排原理
" "C:生物等排原理
" "D:分子模拟原理
" "E:以上答案都对
" "答案:A
"
"抗艾滋病药物AZT的中文名称是
" "A:阿昔洛韦
" "B:司他夫定
" "C:齐多夫定
" "D:拉米夫定
" "E:扎西他滨
" "答案:C
"
"抗艾滋病药物DDC的中文名称是
" "A:阿昔洛韦
" "B:司他夫定
" "C:齐多夫定
" "D:拉米夫定
" "E:扎西他滨
" "答案:E
"
"抗病毒药物Aciclovir的中文名称是
" "A:阿昔洛韦
" "B:司他夫定
" "C:齐多夫定
" "D:拉米夫定
" "E:扎西他滨
" "答案:A
"
"抗病毒药物Ribavirin的中文名称是
" "A:三氮唑核苷
" "B:司他夫定
" "C:齐多夫定
" "D:拉米夫定
" "E:扎西他滨
" "答案:A
"
"碘苷对下列哪种病毒有效
" "A:单纯疱疹病毒
" "B:HIV-Ⅰ
" "C:HIV-Ⅱ
" "D:乙肝病毒
" "E:A型流感病毒
" "答案:A
"
"治疗艾滋病的蛋白酶抑制剂在结构上属于
" "A:多肽类化合物
" "B:大环内酯类化合物
" "C:核苷类化合物
" "D:多烯类化合物
" "E:噻唑环类化合物
" "答案:A
"
"奈韦拉平的作用特点是
" "A:抑制DNA聚合酶的活性
" "B:抑制HIV逆转录酶的活性
" "C:抑制蛋白酶的活性
" "D:抑制RNA聚合酶的活性
" "E:对以上各种酶均有活性
" "答案:B
"
"奈韦拉平在化学结构上属于
" "A:多肽类化合物
" "B:大环内酯类化合物
" "C:核苷类化合物
" "D:多烯类化合物
" "E:二氮卓类化合物