1. It was conceivable that, if three promising concepts (molecular imprinting,
magnetic separation, and optical detection) were combined, a novel fluorescein
isothiocyanate (FITC)-labelled magnetic MIP could be constructed that exhibits
high sensitivity and selectivity.
2. As a reference, non-imprinted polymer coated beads (Fe3O4@SiO2-Dye-NIP),
which did not contain the template, were also prepared in parallel with the
Fe3O4@SiO2-Dye-MIP by using the same synthetic protocol.
3. The polymer layer had a thickness of about 5.7 nm and appeared to be uniform
(top inset), which could be attributable to the intrinsic characteristics of the
controlled/living polymerization mechanism of RAFT.
4. The EDS analysis was also conducted to confirm the existence of imprinted
polymer.
5. When the microspheres are placed in an external magnetic field, efficient
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